Description

Methyl-2-(S)-Biphenyl-2-Aminopropionate is a high-purity chiral intermediate of significant importance in the synthesis of active pharmaceutical ingredients (APIs). Its defined stereochemistry and structural features make it a critical building block for producing enantiomerically pure compounds. This product is essential for research and manufacturing within the pharmaceutical and fine chemical industries, particularly for developers of advanced therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Active Pharmaceutical Ingredient (API) Development: Serves as a crucial precursor in the research and production of enantiomerically pure APIs.
• Asymmetric Synthesis: Used in catalytic and stoichiometric asymmetric reactions to introduce the biphenyl-2-aminopropionate moiety.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals, agrochemicals, and advanced materials requiring specific chirality.
• Research & Development: A valuable compound for medicinal chemistry research, process development, and analytical method development.

Basic Information

Product Name	Methyl-2-(S)-Biphenyl-2-Aminopropionate
CAS No.	63024-30-6
Molecular Formula	C16H17NO2
Molecular Weight	255.31 g/mol
Synonyms	(S)-Methyl 2-amino-2-(biphenyl-2-yl)propanoate; (S)-2-Amino-2-(biphenyl-2-yl)propanoic acid methyl ester; (S)-Methyl 2-(biphenyl-2-yl)alaninate; Methyl (S)-2-amino-2-(2-phenylphenyl)propanoate; (S)-α-Methylbiphenylalanine methyl ester; (S)-2-(Biphenyl-2-yl)alanine methyl ester; (S)-Methyl 2-amino-3-(biphenyl-2-yl)propanoate; (S)-Biphenyl-2-ylalanine methyl ester
EINECS	Contact for details

Quality Control

Our Methyl-2-(S)-Biphenyl-2-Aminopropionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.