Description

trans-2-Phenylcyclopropyl Isocyanate is a specialized, high-purity organic building block featuring a reactive isocyanate group on a constrained cyclopropane ring. This compound matters for its unique structural motif, which is valuable in the synthesis of novel pharmacologically active molecules and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in creating new active ingredients for crop protection with potential novel modes of action.
• Polymer Modification: Serves as a cross-linking agent or monomer for producing specialty polyurethanes and polyurea coatings with tailored properties.
• Chemical Biology Probes: Utilized in the development of activity-based probes (ABPs) for studying enzyme function and inhibition.
• Ligand Synthesis: Intermediate for preparing chiral ligands used in asymmetric catalysis.
• Material Science: Precursor for advanced organic frameworks and functionalized surfaces.

Basic Information

Product Name	trans-2-Phenylcyclopropyl Isocyanate
CAS No.	63009-74-5
Molecular Formula	C10H9NO
Molecular Weight	159.19 g/mol
Synonyms	trans-2-Phenylcyclopropane Isocyanate; (1R,2S)-rel-2-Phenylcyclopropyl Isocyanate; 2-Phenylcyclopropyl Isocyanate (trans-); Isocyanic Acid 2-Phenylcyclopropyl Ester; (trans)-2-Phenyl-1-cyclopropyl Isocyanate; Phenylcyclopropyl Isocyanate; 1-Isocyanato-2-phenylcyclopropane
EINECS	Contact for details

Quality Control

Our trans-2-Phenylcyclopropyl Isocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to consistent quality and traceability supports your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C. This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.