Description

1-Thio-α-D-Glucopyranose Pentaacetate is a key thioglycoside derivative, serving as a versatile building block in synthetic carbohydrate chemistry. Its value lies in its role as a protected thio-sugar precursor, enabling the synthesis of complex glycoconjugates and glycomimetics with high stereochemical control. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical industries, particularly for developing novel therapeutics, diagnostic probes, and bioactive molecules.

Application

• Glycoconjugate Synthesis: A critical intermediate for the preparation of S-linked oligosaccharides, glycopeptides, and glycolipids.
• Pharmaceutical Intermediates: Used in the research and development of glycosidase inhibitors, antiviral agents, and other carbohydrate-based drugs.
• Chemical Biology Tools: Acts as a precursor for synthesizing affinity labels, fluorescent tags, and other probes for studying carbohydrate-protein interactions.
• Agrochemical Development: Employed in creating novel, bioactive sugar derivatives with potential herbicidal or insecticidal properties.
• Material Science: Exploration into functionalized polymers and surfaces via thiol-ene "click" chemistry reactions.

Basic Information

Product Name	1-Thio-α-D-Glucopyranose Pentaacetate
CAS No.	62860-10-0
Molecular Formula	C16H22O10S
Molecular Weight	406.40 g/mol
Synonyms	1-Thio-α-D-glucopyranose pentaacetate; 1-Thio-α-D-glucose pentaacetate; Penta-O-acetyl-1-thio-α-D-glucopyranose; 2,3,4,6-Tetra-O-acetyl-1-thio-α-D-glucopyranose 1-acetate; 1-S-Acetyl-2,3,4,6-tetra-O-acetyl-1-thio-α-D-glucopyranose; α-D-Glucopyranose, 1-thio-, pentaacetate; 1-Thio-α-D-glucopyranosyl acetate tetraacetate
EINECS	263-560-2

Quality Control

Our 1-Thio-α-D-Glucopyranose Pentaacetate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and specific tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability, consistency, and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is stable under inert atmosphere. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Specific Rotation [α]20/D	+160° to +170° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.