Description

1-(Isocyanomethylsulfonyl)-4-Methylbenzene is a specialized organic sulfonyl isocyanate derivative, a high-value intermediate in advanced chemical synthesis. Its unique bifunctional structure, containing both a reactive isocyanate group and a sulfonyl-activated methylene, makes it a critical building block for constructing complex molecular architectures. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonylurea and sulfonamide-based drug candidates, particularly for metabolic and cardiovascular diseases.
• Agrochemical Synthesis: Building block for novel herbicides and fungicides, leveraging the sulfonyl group for enhanced biological activity and selectivity.
• Polymer Modification: Used to introduce reactive isocyanate and sulfone functionalities into polymer chains, improving thermal stability and adhesion properties.
• Cross-linking Agent: Employed in the production of specialty coatings, adhesives, and elastomers that require high-performance cross-linked networks.
• Chemical Research: Valuable reagent in organic and medicinal chemistry for the development of new synthetic methodologies and compound libraries.
• Material Science: Intermediate for creating advanced materials with specific electronic or surface properties.

Basic Information

Product Name	1-(Isocyanomethylsulfonyl)-4-Methylbenzene
CAS No.	62796-16-1
Molecular Formula	C9H9NO3S
Molecular Weight	211.24 g/mol
Synonyms	p-Toluenesulfonylmethyl isocyanate; 4-Methylbenzenesulfonylmethyl isocyanate; (Isocyanomethylsulfonyl)-4-methylbenzene; TosMIC derivative; Toluene-4-sulfonylmethyl isocyanate; 1-Isocyanomethanesulfonyl-4-methylbenzene; α-Isocyanato-p-tolyl sulfone
EINECS	Contact for details

Quality Control

Every batch of 1-(Isocyanomethylsulfonyl)-4-Methylbenzene is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.