Description

4-Cyclobutoxy-Benzoic Acid tert-Butyl Ester is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its molecular structure, featuring a cyclobutyl ether and a protected carboxylic acid group, makes it a versatile synthon for constructing more complex molecules in medicinal chemistry. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of new active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in research targeting central nervous system (CNS) and anti-inflammatory therapies.
• Organic Synthesis Reagent: Used as a protected benzoic acid derivative in multi-step organic synthesis, facilitating complex molecule construction.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and liquid crystals due to its rigid-rod-like molecular structure.
• Agrochemical Intermediate: Potential use in the research and synthesis of next-generation herbicides and plant growth regulators.
• Academic & R&D: A valuable compound for university laboratories and contract research organizations (CROs) conducting exploratory chemistry.

Basic Information

Product Name	4-Cyclobutoxy-Benzoic Acid tert-Butyl Ester
CAS No.	62577-95-1
Molecular Formula	C15H20O3
Molecular Weight	248.32 g/mol
Synonyms	tert-Butyl 4-cyclobutoxybenzoate; Benzoic acid, 4-cyclobutoxy-, 1,1-dimethylethyl ester; 4-Cyclobutoxybenzoic acid tert-butyl ester; 1,1-Dimethylethyl 4-cyclobutoxybenzoate; p-Cyclobutoxybenzoic acid tert-butyl ester; 4-(Cyclobutyloxy)benzoic acid tert-butyl ester; tert-Butyl 4-(cyclobutyloxy)benzoate
EINECS	Contact for details

Quality Control

Our 4-Cyclobutoxy-Benzoic Acid tert-Butyl Ester is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent identity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality systems support development from research quantities to commercial scale, ensuring reliable supply for critical R&D and production timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.