Description

3-o-Acetyloleanderolide is a specific acetylated derivative of oleanderolide, a cardenolide-type natural product. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its potential as a key intermediate or a bioactive scaffold. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel therapeutic agents or the study of cardiac glycoside analogs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel cardenolide derivatives for biological evaluation.
• Medicinal Chemistry Research: Used as a reference standard or a starting material in structure-activity relationship (SAR) studies targeting specific biological pathways.
• Biochemical Tool Compound: Employed in in-vitro assays to investigate the mechanism of action of cardiac glycosides and their interaction with Na+/K+-ATPase.
• Natural Product Synthesis: A key intermediate in the total or semi-synthesis of complex natural products belonging to the cardenolide family.
• Academic Research: Utilized in university and institutional labs for teaching and research in advanced organic chemistry and natural product chemistry.

Basic Information

Product Name	3-o-Acetyloleanderolide
CAS No.	62498-83-3
Molecular Formula	C32H48O9
Molecular Weight	576.73 g/mol
Synonyms	3-O-Acetyloleanderolide; 16β-Acetoxy-12β,14β-dihydroxy-5β-card-20(22)-enolide; Oleandrigenin 3-acetate; 16-Acetylgitoxigenin; Acetyloleandrin; 16β-Acetoxygitoxigenin; 3-O-Acetyl-16β-hydroxygitoxigenin
EINECS	Contact for details

Quality Control

Our 3-o-Acetyloleanderolide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product should be kept under inert conditions if long-term stability is required.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.