Description

5,6,7,8-Tetrahydro-2-Methyl-Pyrido[3,4-D]Pyrimidin-4(3H)-One Dihydrochloride is a high-purity, pharmaceutically relevant heterocyclic compound supplied as a dihydrochloride salt. This compound serves as a critical synthetic intermediate or active pharmaceutical ingredient (API) in advanced research and development. It is essential for medicinal chemistry programs, particularly those focused on central nervous system (CNS) targets and kinase inhibition. Industrial buyers in pharmaceutical R&D and fine chemical synthesis require this material for its defined structure and reliable quality to ensure successful downstream processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and optimizing potent and selective kinase inhibitors.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Utilized in vitro studies to investigate biological pathways and enzyme functions.
• Fine Chemical Synthesis: An advanced intermediate for the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	5,6,7,8-Tetrahydro-2-Methyl-Pyrido[3,4-D]Pyrimidin-4(3H)-One Dihydrochloride
CAS No.	62260-00-8
Molecular Formula	C9H14N4O • 2HCl
Molecular Weight	279.16 g/mol
Synonyms	2-Methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one dihydrochloride; 5,6,7,8-Tetrahydro-2-methyl-4(3H)-pyrimidinone dihydrochloride; Tetrahydro-2-methylpyrido[3,4-d]pyrimidin-4-one dihydrochloride; 62260-00-8; 2-Methyl-4-oxo-3,4,5,6,7,8-hexahydro-pyrido[3,4-d]pyrimidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-2-Methyl-Pyrido[3,4-D]Pyrimidin-4(3H)-One Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.