Description

5-Bromo-Thiophene-2-Carboxylic Acid Methyl Ester is a versatile brominated thiophene derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its reactive bromine substituent and ester functionality, enabling precise molecular construction. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the thiophene scaffold for bioactivity.
• Material Science Precursor: Serves as a monomer or precursor in the development of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A fundamental reagent in academic and industrial R&D for heterocyclic chemistry, cross-coupling reactions (e.g., Suzuki, Stille), and structure-activity relationship (SAR) studies.
• Dye and Pigment Industry: Intermediate for synthesizing specialized dyes and pigments with specific light-absorption properties.

Basic Information

Product Name	5-Bromo-Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	62224-19-5
Molecular Formula	C7H5BrO2S
Molecular Weight	221.08 g/mol
Synonyms	Methyl 5-bromothiophene-2-carboxylate; 5-Bromo-2-thiophenecarboxylic acid methyl ester; 2-Bromo-5-(methoxycarbonyl)thiophene; Methyl 5-bromo-2-thiophenecarboxylate; 5-Bromothiophene-2-carboxylic acid methyl ester; 5-Bromo-2-thiophenecarboxylic acid, methyl ester; Methyl 5-bromothiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Bromo-Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and production applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.