Description

1,2,3,4-Tetra-o-Acetyl--D-Glucuronic Acid CAS NO 62133-77-1 is a key acetylated derivative of D-glucuronic acid, serving as a vital protected intermediate in synthetic organic chemistry. Its primary value lies in enabling the controlled synthesis of complex glycosides, glycoconjugates, and other bioactive molecules where the glucuronic acid moiety is required. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for developing prodrugs, drug metabolites, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of glucuronide prodrugs and targeted drug delivery systems.
• Glycoconjugate Synthesis: Used in the preparation of complex oligosaccharides, glycoproteins, and glycolipids for research and therapeutic applications.
• Biochemical Research: Serves as a precursor in enzymatic and chemical studies of glucuronidation pathways and metabolite formation.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring protected sugar acids.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1,2,3,4-Tetra-o-Acetyl--D-Glucuronic Acid
CAS No.	62133-77-1
Molecular Formula	C14H18O11
Molecular Weight	362.29 g/mol
Synonyms	D-Glucuronic Acid, 1,2,3,4-Tetraacetate; Tetra-O-acetyl-D-glucuronic Acid; 1,2,3,4-Tetra-O-acetyl-β-D-glucopyranuronic Acid; (2S,3S,4S,5R,6R)-3,4,5-Triacetoxy-6-(carboxy)oxan-2-yl Methyl Acetate; Acetylated D-Glucuronic Acid; Glucuronic Acid Tetraacetate
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetra-o-Acetyl--D-Glucuronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.