Description

Dulofibrate is a high-purity chemical intermediate with significant relevance in advanced pharmaceutical synthesis. Its primary value lies in its role as a key building block for the development of lipid-regulating agents and other active pharmaceutical ingredients (APIs). This compound is essential for research and development laboratories, process chemists, and manufacturers operating within the global pharmaceutical and fine chemical sectors. Dulofibrate CAS NO 61887-16-9 is supplied under stringent quality controls to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Primary use as a crucial precursor in the synthesis of fibrate-class lipid-modulating agents.
• Active Pharmaceutical Ingredient (API) Research: Serves as a key starting material or intermediate in R&D for new cardiovascular and metabolic disease therapeutics.
• Process Chemistry & Scale-Up: Used in process development and optimization studies within fine chemical and contract manufacturing organizations (CMOs).
• Reference Standard: Suitable for use as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Employed in studies investigating peroxisome proliferator-activated receptor (PPAR) pathways and related mechanisms.

Basic Information

Product Name	Dulofibrate
CAS No.	61887-16-9
Molecular Formula	C21H24O5
Molecular Weight	356.41 g/mol
Synonyms	2-(4-(2-(4-Chlorophenoxy)-2-methylpropanoyl)phenoxy)-2-methylpropanoic Acid; Chlofibric Acid Isobutyl Ester Derivative; Duolip; Clofibrate Analog; CL 90279; Propanoic acid, 2-[4-[2-(4-chlorophenoxy)-2-methyl-1-oxopropoxy]phenoxy]-2-methyl-; 2-Methyl-2-[4-[(2-methyl-2-[(4-chlorophenoxy)carbonyl]propyl)oxy]phenoxy]propanoic Acid
EINECS	Contact for details

Quality Control

Our Dulofibrate is manufactured under a cGMP-compliant quality management system, ensuring it meets the rigorous standards required for pharmaceutical intermediates. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC and GC. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.