Description

n-(Trimethylsilyl)-2,2-Dimethylpropane-1-Imine is a specialized organosilicon reagent featuring a sterically hindered imine functional group. This compound is valued for its role as a versatile silylating agent and a protected form of a primary amine, enabling selective transformations in complex synthetic pathways. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for the synthesis of active pharmaceutical ingredients (APIs) and novel silicon-containing polymers.

Application

• Pharmaceutical Intermediate Synthesis: Acts as a key building block and protecting group for primary amines in multi-step API synthesis.
• Organosilicon Chemistry: Serves as a precursor for introducing the trimethylsilyl (TMS) group into target molecules.
• Catalyst and Ligand Preparation: Used in the development of novel catalysts and ligands for asymmetric synthesis.
• Polymer Modification: Employed to functionalize polymers, enhancing properties like solubility or thermal stability.
• Agrochemical Research: Utilized in the synthesis of novel crop protection agents and plant growth regulators.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic and organometallic chemistry.

Basic Information

Product Name	n-(Trimethylsilyl)-2,2-Dimethylpropane-1-Imine
CAS No.	61860-99-9
Molecular Formula	C8H19NSi
Molecular Weight	157.33 g/mol
Synonyms	Neopentylidene(trimethylsilyl)amine; 2,2-Dimethylpropylidene(trimethylsilyl)amine; (2,2-Dimethylpropylidene)(trimethylsilyl)amine; Trimethyl(2,2-dimethylpropylideneamino)silane; TMS-Neopentylideneamine; N-(Trimethylsilyl)-2,2-dimethylpropanimine; N-(Trimethylsilyl)neopentylideneamine; N-Trimethylsilyl-2,2-dimethylpropylideneimine
EINECS	Contact for details

Quality Control

Our n-(Trimethylsilyl)-2,2-Dimethylpropane-1-Imine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to verify identity, potency, and moisture content. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.