Description

2-Trifluoromethanesulfonyloxyaceticacidethylester is a high-value trifluoromethanesulfonate (triflate) ester derivative, serving as a versatile and reactive synthetic intermediate. Its core value proposition lies in its ability to act as an efficient alkylating agent and a key building block for introducing functionalized acetic acid moieties into complex molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials where precise molecular modification is required.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for introducing ester-protected carboxylic acid functionalities.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific fluorinated or sulfonated components.
• Organic Synthesis Reagent: Functions as an effective alkylating agent and a precursor for generating other triflate derivatives in complex multi-step organic reactions.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and advanced organic electronic materials due to its unique electronic properties.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing complex carbon-carbon bonds.
• Fluorine Chemistry: A valuable reagent in organofluorine chemistry for the preparation of compounds with tailored physicochemical properties.

Basic Information

Product Name	2-Trifluoromethanesulfonyloxyaceticacidethylester
CAS No.	61836-02-0
Molecular Formula	C5H7F3O5S
Molecular Weight	236.17 g/mol
Synonyms	Ethyl 2-[(trifluoromethyl)sulfonyl]oxyacetate; Ethyl (trifluoromethanesulfonyloxy)acetate; Acetic acid, 2-[(trifluoromethyl)sulfonyl]oxy-, ethyl ester; Trifluoromethanesulfonic acid 2-ethoxy-2-oxoethyl ester; Ethyl glycolate triflate; 2-(Triflyloxy)acetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethanesulfonyloxyaceticacidethylester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening containers to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.