Description

(17R)-11α-Methoxy-19-Norpregna-1,3,5(10)-Trien-20-Yne-3,17-Diol CAS NO 61665-15-4 is a high-purity synthetic steroid derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in providing a structurally defined and reliable building block for the research and development of novel therapeutic agents. This compound is essential for pharmaceutical manufacturers and R&D laboratories focused on endocrinology, oncology, and metabolic disease research, where precise chemical structure is paramount for biological activity and regulatory approval.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of novel steroid-based drugs and hormonal therapies.
• Research & Development: Used in academic and industrial R&D for studying steroid receptor interactions, metabolic pathways, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (e.g., HPLC, LC-MS).
• Preclinical Studies: Utilized in the development and testing of new chemical entities (NCEs) for various therapeutic areas, including cancer and endocrine disorders.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for complex steroid molecules within GMP environments.

Basic Information

Product Name	(17R)-11α-Methoxy-19-Norpregna-1,3,5(10)-Trien-20-Yne-3,17-Diol
CAS No.	61665-15-4
Molecular Formula	C21H26O3
Molecular Weight	326.43 g/mol
Synonyms	11α-Methoxy-19-norpregna-1,3,5(10)-trien-20-yne-3,17β-diol; (17R)-11α-Methoxyestra-1,3,5(10)-trien-20-yne-3,17-diol; 11α-Methoxy-19-nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17β-diol; 11-Methoxy-19-norpregna-1,3,5(10)-trien-20-yne-3,17-diol; 11α-Methoxy-19-norpregna-1,3,5(10)-trien-20-yn-3,17β-diol; NSC 83688
EINECS	Contact for details

Quality Control

Our (17R)-11α-Methoxy-19-Norpregna-1,3,5(10)-Trien-20-Yne-3,17-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.