Description

Ethyl (1R,2S)-cis-2-Hydroxycyclopentanecarboxylate is a high-purity chiral building block of significant importance in asymmetric synthesis. This compound matters because it provides a stereochemically defined scaffold for constructing complex molecules with precise three-dimensional architecture. Pharmaceutical and fine chemical R&D teams need it for the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials where stereochemical control is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of prostaglandin analogs, antiviral agents, and other bioactive molecules.
• Asymmetric Catalysis Ligand Precursor: Used to develop novel chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating stereospecific herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Ethyl (1R,2S)-cis-2-Hydroxycyclopentanecarboxylate
CAS No.	61586-79-6
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(1R,2S)-Ethyl 2-hydroxycyclopentanecarboxylate; cis-(1R,2S)-Ethyl 2-hydroxycyclopentanecarboxylate; Ethyl (1R,2S)-2-hydroxycyclopentanecarboxylate; (-)-Ethyl cis-2-hydroxycyclopentanecarboxylate; (1R,2S)-2-Hydroxycyclopentanecarboxylic acid ethyl ester; cis-2-Hydroxycyclopentanecarboxylic acid ethyl ester (enantiomer)
EINECS	Contact for details

Quality Control

Our Ethyl (1R,2S)-cis-2-Hydroxycyclopentanecarboxylate is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, enantiomeric excess (ee), and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.