Description

Thymosin α1 CAS NO 61512-21-8 is a synthetic, 28-amino acid peptide fragment of the naturally occurring thymosin α-1 protein, known for its potent immunomodulatory properties. This high-purity peptide is critical for research and development in advanced immunotherapies and as a key intermediate in pharmaceutical manufacturing. It is primarily utilized by biotechnology firms, pharmaceutical R&D laboratories, and manufacturers of active pharmaceutical ingredients (APIs) for applications in oncology, infectious diseases, and vaccine adjuvants.

Application

• Pharmaceutical API Intermediate: Serves as a critical building block in the synthesis of finished immunomodulatory drug products.
• Immunology Research: Used in preclinical and clinical studies to investigate mechanisms of immune response, T-cell activation, and cytokine regulation.
• Oncology Therapeutics: Employed in the development of adjunctive therapies to enhance immune response in cancer treatment protocols.
• Infectious Disease Treatment: Applied in research for therapies targeting chronic viral infections such as Hepatitis B and C.
• Vaccine Adjuvant Development: Investigated for its potential to improve the efficacy of vaccines by modulating the immune system.
• Cell Culture & Diagnostics: Utilized in specialized cell culture media and diagnostic assay development for immune function testing.

Basic Information

Product Name	Thymosin α1
CAS No.	61512-21-8
Molecular Formula	C129H215N33O55
Molecular Weight	3108.28 g/mol
Synonyms	Thymalfasin; Thymosin α-1; Tα1; Synthetic Thymosin Alpha 1; Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH; ZADAXIN® (brand name); Immunomodulatory peptide 1
EINECS	Contact for details

Quality Control

Our Thymosin α1 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and stringent tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, store at 2-8°C. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0% (Total Peptide Content)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.