Description

7,8-Dimethoxy-2,3,4,5-Tetrahydro-1H-Benzo[E][1,4]Diazepine is a high-purity, synthetically derived benzodiazepine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and a versatile scaffold for the creation of novel bioactive molecules. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of potential therapeutic agents targeting neurological and psychiatric conditions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine-based drug candidates for central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new pharmacophores with targeted receptor affinity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Development: Employed in the early-stage development of potential anxiolytic, sedative, or muscle relaxant compounds.
• Chemical Biology Probes: Utilized in biochemical assays to study GABA-A receptor interactions and related neurological pathways.
• Academic Research: A valuable compound for universities and research institutes studying heterocyclic chemistry and neuropharmacology.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	7,8-Dimethoxy-2,3,4,5-Tetrahydro-1H-Benzo[E][1,4]Diazepine
CAS No.	61471-52-1
Molecular Formula	C₁₃H₁₈N₂O₂
Molecular Weight	234.30 g/mol
Synonyms	7,8-Dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepine; 1H-3-Benzazepine, 7,8-dimethoxy-2,3,4,5-tetrahydro-; 7,8-Dimethoxy-1,2,4,5-tetrahydro-3H-3-benzazepine; 7,8-Dimethoxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine; Benzo[e][1,4]diazepine, 7,8-dimethoxy-2,3,4,5-tetrahydro-1H-; Tetrahydrobenzodiazepine derivative
EINECS	Contact for details

Quality Control

Our 7,8-Dimethoxy-2,3,4,5-Tetrahydro-1H-Benzo[E][1,4]Diazepine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP guidelines where applicable, ensuring suitability for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed under inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.