Description

(2R)-2-Pyrrolidineacetic Acid Methyl Ester CAS NO 61376-53-2 is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. Its value lies in its role as a key building block for the synthesis of complex, biologically active molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials that require precise stereochemical control.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of various APIs, including potential treatments for neurological disorders and cardiovascular diseases.
• Agrochemical Synthesis: Used in the research and production of advanced, stereoselective pesticides and herbicides.
• Asymmetric Catalysis: Serves as a precursor or ligand for chiral catalysts used in enantioselective synthesis.
• Peptidomimetics & Drug Discovery: A valuable scaffold in medicinal chemistry for creating novel peptide-like compounds and probing biological targets.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and complex organic molecules.
• Academic & Industrial R&D: A key reagent for method development and exploratory synthesis in chemistry laboratories worldwide.

Basic Information

Product Name	(2R)-2-Pyrrolidineacetic Acid Methyl Ester
CAS No.	61376-53-2
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	Methyl (R)-(-)-2-Pyrrolidineacetate; (R)-(-)-2-Pyrrolidineacetic Acid Methyl Ester; (R)-Methyl 2-(Pyrrolidin-2-yl)acetate; (2R)-2-Pyrrolidineacetic Acid, Methyl Ester; L-Proline Methyl Ester Derivative; (R)-Proline Methyl Ester Homolog; Methyl (R)-2-Pyrrolidinylacetate
EINECS	Contact for details

Quality Control

Our (2R)-2-Pyrrolidineacetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.