Description

1-(2-Chloroethyl)-3-(4α-Methoxycyclohexan-1α-Yl)-1-Nitrosourea is a specialized nitrosourea derivative, a class of compounds known for their alkylating properties. This compound is of significant interest for advanced research and development in medicinal chemistry and oncology. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel therapeutic agents. The product is supplied with a high level of purity and batch-to-batch consistency to support critical synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of potential alkylating chemotherapeutic agents.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of DNA alkylation and cytotoxicity.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new analogs with improved efficacy and reduced toxicity profiles.
• Bioconjugation Studies: Potential use in developing targeted drug delivery systems due to its reactive functional groups.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in organic synthesis and cancer biology.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-(2-Chloroethyl)-3-(4α-Methoxycyclohexan-1α-Yl)-1-Nitrosourea
CAS No.	61367-30-4
Molecular Formula	C10H16ClN3O3
Molecular Weight	261.71 g/mol
Synonyms	1-(2-Chloroethyl)-3-(4-methoxycyclohexyl)-1-nitrosourea; 1-Nitrosourea, 1-(2-chloroethyl)-3-(4-methoxycyclohexyl)-; 1-(2-Chloroethyl)-3-(trans-4-methoxycyclohexyl)-1-nitrosourea; NSC 338947; Nitrosourea CCNU analog; Lomustine analog; Cyclohexyl nitrosourea derivative
EINECS	Contact for details

Quality Control

Our 1-(2-Chloroethyl)-3-(4α-Methoxycyclohexan-1α-Yl)-1-Nitrosourea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a dry, cool, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.