Description

(E)-1-[2,3-Dihydro-4-Hydroxy-2-(1-Hydroxy-1-Methylethyl)Benzofuran-5-Yl]-3-Phenyl-2-Propen-1-One is a high-purity, synthetic organic compound belonging to the benzofuran class, valued for its role as a key chiral intermediate and building block in advanced chemical synthesis. Its defined stereochemistry and functional groups make it a critical precursor for developing active pharmaceutical ingredients (APIs) and fine chemicals with specific biological activity. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex molecular architectures.
• Agrochemical Research: Used in the development and production of advanced pesticides, herbicides, and plant growth regulators where specific stereochemistry is essential for activity.
• Fine Chemical Synthesis: Acts as a versatile precursor for creating complex molecules used in material science, dyes, and functional polymers.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies in organic synthesis, asymmetric catalysis, and medicinal chemistry.
• Process Chemistry: Utilized in optimizing and scaling up synthetic routes for commercial production, where consistent quality and purity are paramount.

Basic Information

Product Name	(E)-1-[2,3-Dihydro-4-Hydroxy-2-(1-Hydroxy-1-Methylethyl)Benzofuran-5-Yl]-3-Phenyl-2-Propen-1-One
CAS No.	61235-35-6
Molecular Formula	C20H20O4
Molecular Weight	324.37 g/mol
Synonyms	(E)-1-(4-Hydroxy-2-(2-hydroxypropan-2-yl)-2,3-dihydrobenzofuran-5-yl)-3-phenylprop-2-en-1-one; 2-Propen-1-one, 1-[2,3-dihydro-4-hydroxy-2-(1-hydroxy-1-methylethyl)-5-benzofuranyl]-3-phenyl-, (E)-; 5-Benzofuranpropenone derivative; Dihydrobenzofuranyl propenone; Chiral benzofuran intermediate; (E)-enantiomer of CAS 61235-35-6
EINECS	Contact for details

Quality Control

Our production of (E)-1-[2,3-Dihydro-4-Hydroxy-2-(1-Hydroxy-1-Methylethyl)Benzofuran-5-Yl]-3-Phenyl-2-Propen-1-One adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial identification methods, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its sensitivity to oxidation, prolonged storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.