Description

3-Ethyl-1,3-Bis(Trimethylsilyl)-1-Pentyne is a specialized organosilicon compound featuring a unique combination of an alkyne moiety and two trimethylsilyl protecting groups. This structure makes it a valuable protected acetylene synthon and a versatile building block in advanced organic synthesis. It is primarily used by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Advanced Organic Synthesis: A key protected intermediate for the controlled introduction of acetylene units in multi-step syntheses of active pharmaceutical ingredients (APIs) and fine chemicals.
• Pharmaceutical Research: Used in the development of novel drug candidates, particularly in creating carbon-carbon bonds via Sonogashira and other cross-coupling reactions.
• Agrochemical Development: Serves as a building block for synthesizing novel pesticides and herbicides with specific structural motifs.
• Material Science: A precursor for synthesizing silicon-containing polymers, dendrimers, or molecular wires with tailored electronic properties.
• Academic & Industrial R&D: A valuable reagent for methodology development in organometallic chemistry and catalysis studies.

Basic Information

Product Name	3-Ethyl-1,3-Bis(Trimethylsilyl)-1-Pentyne
CAS No.	61227-91-6
Molecular Formula	C13H28Si2
Molecular Weight	240.53 g/mol
Synonyms	1-Pentyne, 3-ethyl-1,3-bis(trimethylsilyl)-; 3-Ethyl-1,3-bis(trimethylsilyl)-1-pentyne; 3-Ethyl-1,3-bis(trimethylsilyl)pentyne; 1,3-Bis(trimethylsilyl)-3-ethyl-1-pentyne; TMS-protected acetylene derivative; Ethylbis(trimethylsilyl)propargyl compound
EINECS	Contact for details

Quality Control

Our production of 3-Ethyl-1,3-Bis(Trimethylsilyl)-1-Pentyne adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by modern analytical techniques including GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.