Description

3,3-Diethyl-1-Trimethylsilyl-1-Pentyne is a specialized organosilicon building block featuring a terminal alkyne protected by a trimethylsilyl (TMS) group. This compound is valued for its role as a versatile synthetic intermediate in advanced organic and organometallic chemistry, enabling precise carbon-carbon bond formation. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates via Sonogashira and other cross-coupling reactions.
• Agrochemical Synthesis: Serves as a key building block for creating novel pesticides, herbicides, and fungicides with specific biological activity.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers with tailored electronic or optical properties.
• Organic Synthesis Reagent: Acts as a protected acetylene equivalent in multi-step synthetic sequences, offering stability and selective deprotection.
• Catalyst & Ligand Development: Utilized in the preparation of novel metal-organic frameworks (MOFs) and catalytic complexes.
• Academic & Industrial R&D: A critical reagent for methodology development and exploring new chemical spaces in research laboratories.

Basic Information

Product Name	3,3-Diethyl-1-Trimethylsilyl-1-Pentyne
CAS No.	61227-90-5
Molecular Formula	C12H24Si
Molecular Weight	196.41 g/mol
Synonyms	1-Trimethylsilyl-3,3-diethyl-1-pentyne; 3,3-Diethyl-1-(trimethylsilyl)-1-pentyne; (3,3-Diethylpent-1-yn-1-yl)trimethylsilane; TMS-Protected 3,3-Diethylpentyne; Trimethyl(3,3-diethylpent-1-yn-1-yl)silane
EINECS	Contact for details

Quality Control

Our production of 3,3-Diethyl-1-Trimethylsilyl-1-Pentyne adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.