Description

Triethyl Phosphonoacetate-1-13C is a stable isotope-labeled analog of triethyl phosphonoacetate, where the carbon-13 label is specifically positioned at the 1-carbonyl position. This compound is a critical reagent in organic synthesis, particularly for the preparation of isotopically labeled compounds used in metabolic and pharmacokinetic studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise isotopic labeling for analytical and developmental purposes.

Application

• Synthesis of 13C-Labeled Pharmaceuticals: A key building block for creating isotopically labeled active pharmaceutical ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Pathway Tracing: Used to synthesize probes for tracking biochemical pathways using techniques like NMR spectroscopy and mass spectrometry.
• Development of Labeled Agrochemicals: Employed in the research and development of isotopically labeled pesticides and herbicides to study environmental fate and degradation.
• Organic Synthesis Reagent: Functions as a labeled Horner-Wadsworth-Emmons reagent for the synthesis of α,β-unsaturated esters and other complex molecules with a 13C tag.
• Material Science Research: Used in the preparation of labeled monomers or intermediates for advanced polymers and materials where isotopic composition is studied.
• Internal Standards for Analytics: Serves as a precursor for synthesizing high-purity internal standards used in quantitative LC-MS and GC-MS analysis.

Basic Information

Product Name	Triethyl Phosphonoacetate-1-13C
CAS No.	61203-67-6
Molecular Formula	C8H1713CO5P
Molecular Weight	Contact for details
Synonyms	(Triethoxyphosphoryl)acetic-1-13C acid ethyl ester; Triethyl (1-13C)phosphonoacetate; Ethyl (diethoxyphosphoryl)acetate-1-13C; Diethyl (ethoxy(oxo)acetate-1-13C)phosphonate; Triethyl PAA-1-13C; 13C1-Triethyl phosphonoacetate; [1-13C]Triethyl phosphonoacetate; Acetic-1-13C acid, 2-(triethoxyphosphinyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Triethyl Phosphonoacetate-1-13C is produced under strict quality management protocols. Each batch is characterized to ensure high chemical purity and isotopic enrichment, with specifications typically covering isotopic purity (atom % 13C), chemical purity (by NMR and HPLC), and identity confirmation. Certificates of Analysis (COA) detailing these parameters are provided and available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97%
Isotopic Purity (atom % 13C)	≥ 99%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.