Description

Propargyl Triethylsilyl Ether (CAS NO 61157-25-3) is a versatile organosilicon reagent featuring a protected propargyl alcohol functionality. This compound is valued for its role as a key synthetic intermediate in advanced organic synthesis, enabling the introduction of the propargyl group under mild conditions. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly in nucleoside and antiviral drug development.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators.
• Material Science: A precursor in the development of specialty polymers, dendrimers, and silicon-containing advanced materials.
• Cross-Coupling Reactions: Employed in Sonogashira and other palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Natural Product Synthesis: Facilitates the construction of complex natural products and bioactive molecules in academic and industrial research.
• Ligand and Catalyst Development: Used to prepare novel ligands for asymmetric catalysis and organometallic complexes.

Basic Information

Product Name	Propargyl Triethylsilyl Ether
CAS No.	61157-25-3
Molecular Formula	C9H18OSi
Molecular Weight	170.32 g/mol
Synonyms	Triethylsilyl Propargyl Ether; (Triethylsilyloxy)prop-1-yne; 1-(Triethylsilyloxy)-2-propyne; Propargyloxy-triethyl-silane; Propargyl alcohol triethylsilyl ether; TES Propargyl Ether; 2-Propyn-1-ol, 1-(triethylsilyl)-; 1-(Triethylsilyl)-2-propyn-1-ol
EINECS	Contact for details

Quality Control

Our Propargyl Triethylsilyl Ether is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and away from heat and ignition sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.