Description

(S)-Ethyl 1-Bromo-1-Phenyl Acetate is a high-value chiral building block, specifically the (S)-enantiomer of ethyl bromophenylacetate. This compound is essential for the stereoselective synthesis of complex molecules, enabling the creation of single-enantiomer products with high optical purity. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing chiral centers in active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Used in stereocontrolled reactions such as asymmetric alkylations and Reformatsky-type reactions to introduce chiral α-carbon centers.
• Agrochemical Research: Building block for developing chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in homogeneous catalysis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring specific stereochemistry.
• Academic & Contract Research: Critical reagent for methodological development in organic chemistry and for producing reference standards in analytical laboratories.

Basic Information

Product Name	(S)-Ethyl 1-Bromo-1-Phenyl Acetate
CAS No.	61139-20-6
Molecular Formula	C10H11BrO2
Molecular Weight	243.10 g/mol
Synonyms	(S)-Ethyl α-Bromophenylacetate; (S)-Ethyl 2-Bromo-2-phenylacetate; (S)-Bromo(phenyl)acetic Acid Ethyl Ester; Ethyl (S)-(-)-α-Bromophenylacetate; (S)-1-Bromo-1-phenylethyl acetate; L-(-)-Ethyl α-Bromophenylacetate; (S)-Bromophenylacetic Acid Ethyl Ester; (S)-Ethyl Bromo(phenyl)acetate
EINECS	Contact for details

Quality Control

Our (S)-Ethyl 1-Bromo-1-Phenyl Acetate is manufactured under cGMP guidelines and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high enantiomeric purity. Our quality commitment includes comprehensive identity, purity, and chiral integrity verification. Certificates of Analysis (COA) detailing specific results for chiral purity (HPLC), chemical purity (GC/HPLC), and identity (NMR, IR) are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (S-enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.