Description

4α-[3-(2-Fluoroethyl)-3-Nitrosoureido]-1α-Cyclohexanecarboxylic Acid is a specialized synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its unique molecular structure, featuring a fluorinated nitrosourea moiety, makes it a critical building block for the synthesis of novel therapeutic agents, particularly in oncology and targeted drug discovery. This high-purity compound is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of next-generation treatments.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel anticancer agents and other biologically active molecules.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Preclinical Studies: Serves as a starting material or reference standard in the development of fluorinated drug candidates.
• Chemical Biology: Employed as a tool compound to study enzyme inhibition or receptor binding mechanisms involving nitrosourea functionalities.
• Custom Synthesis: A building block for contract manufacturing and the production of high-value, low-volume specialty chemicals.

Basic Information

Product Name	4α-[3-(2-Fluoroethyl)-3-Nitrosoureido]-1α-Cyclohexanecarboxylic Acid
CAS No.	61137-62-0
Molecular Formula	C10H15FN3O4
Molecular Weight	260.24 g/mol
Synonyms	1α-Cyclohexanecarboxylic acid, 4α-[3-(2-fluoroethyl)-3-nitrosoureido]-; 4α-[N-(2-Fluoroethyl)-N-nitrosoureido]-1α-cyclohexanecarboxylic Acid; 4α-[3-(2-Fluoroethyl)-3-nitrosoureido]-1α-cyclohexanecarboxylic Acid; 4α-[3-(2-Fluoroethyl)-3-nitrosoureido]cyclohexanecarboxylic Acid; 1α,4α-Cyclohexanedicarboxylic acid derivative; Fluoroethyl nitrosourea cyclohexanecarboxylic acid; FENU-CA (abbreviation).
EINECS	Contact for details

Quality Control

Our 4α-[3-(2-Fluoroethyl)-3-Nitrosoureido]-1α-Cyclohexanecarboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.