Description

cis-1,4-Cyclohexylenebis(3-(2-Chloroethyl)-3-Nitrosourea) CAS NO 61137-59-5 is a specialized nitrosourea derivative with a unique bifunctional cyclohexylene bridge. This compound is valued for its role as a key intermediate in advanced organic synthesis and pharmaceutical research, particularly in the development of novel alkylating agents. It is primarily sought by research institutions and chemical manufacturers engaged in the development of targeted therapeutic compounds and high-value specialty chemicals.

Application

• Pharmaceutical intermediate for the research and development of novel chemotherapeutic agents.
• Key building block in organic synthesis for creating complex, multi-functional molecules.
• Precursor in the study of nitrosourea-based alkylating agents and their mechanisms of action.
• Research chemical for academic and industrial investigations into cancer biology and drug discovery.
• Specialty intermediate for fine chemical and agrochemical synthesis requiring specific stereochemistry.
• Reference standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	cis-1,4-Cyclohexylenebis(3-(2-Chloroethyl)-3-Nitrosourea)
CAS No.	61137-59-5
Molecular Formula	C₁₃H₂₀Cl₂N₄O₄
Molecular Weight	367.23 g/mol
Synonyms	1,4-cis-Bis(3-(2-chloroethyl)-3-nitrosoureido)cyclohexane; Cyclohexane-1,4-diyl bis(3-(2-chloroethyl)-1-nitrosourea); cis-1,4-BCNU; cis-1,4-Bis(3-(2-chloroethyl)-3-nitrosoureido)cyclohexane; cis-Cyclohexyl BCNU; NSC 603070
EINECS	Contact for details

Quality Control

Our cis-1,4-Cyclohexylenebis(3-(2-Chloroethyl)-3-Nitrosourea) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP standards for pharmaceutical intermediates, and specifications can be tailored to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.