Description

1-(2-Chloroethyl)-3-(4β-Chloromethylcyclohexan-1α-Yl)-1-Nitrosourea is a specialized nitrosourea derivative with a complex bifunctional alkylating structure. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a key intermediate in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology and targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of experimental chemotherapeutic agents and targeted cancer therapies.
• Biomedical Research: Used in academic and industrial laboratories to study alkylating agent mechanisms, DNA cross-linking, and structure-activity relationships (SAR).
• Oncology Drug Discovery: A key precursor for developing novel nitrosourea-based compounds with potential antitumor activity.
• Bioconjugation Studies: Employed in research exploring the attachment of cytotoxic payloads to antibodies or other targeting molecules (ADC research).
• Chemical Biology Probes: Utilized to create molecular tools for investigating cellular pathways and enzyme functions.

Basic Information

Product Name	1-(2-Chloroethyl)-3-(4β-Chloromethylcyclohexan-1α-Yl)-1-Nitrosourea
CAS No.	61137-51-7
Molecular Formula	C11H19Cl2N3O2
Molecular Weight	296.19 g/mol
Synonyms	1-(2-Chloroethyl)-3-(4β-chloromethylcyclohex-1α-yl)-1-nitrosourea; 1-Nitrosourea, 1-(2-chloroethyl)-3-(4β-chloromethyl-1α-cyclohexyl)-; 3-(4β-Chloromethyl-1α-cyclohexyl)-1-(2-chloroethyl)-1-nitrosourea; CCNU derivative; Cyclohexyl nitrosourea analog; Chloroethylnitrosourea intermediate; Lomustine analog
EINECS	Contact for details

Quality Control

Our 1-(2-Chloroethyl)-3-(4β-Chloromethylcyclohexan-1α-Yl)-1-Nitrosourea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reproducible results in critical discovery workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to the light-sensitive and potentially moisture-sensitive nature of nitrosourea compounds, the container should be kept in a secondary protective enclosure. For long-term storage, consider inert atmosphere conditions. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.