Description

7α-(Trimethylsiloxy)Androst-4-Ene-3,17-Dione is a key steroidal intermediate characterized by its unique trimethylsiloxy group at the 7-alpha position. This compound is of significant commercial importance as a versatile building block in the synthesis of more complex steroid-based pharmaceuticals and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of advanced steroid-based drugs, including potential anti-inflammatory and hormonal agents.
• Research & Development: Used in academic and industrial laboratories for exploring new synthetic pathways and studying steroid chemistry and metabolism.
• Fine Chemical Synthesis: Serves as a specialized building block for creating high-value, complex molecules in custom synthesis and process development.
• Biochemical Research: Employed in studies related to enzyme inhibition, receptor binding assays, and metabolic pathway analysis due to its modified steroid structure.

Basic Information

Product Name	7α-(Trimethylsiloxy)Androst-4-Ene-3,17-Dione
CAS No.	61103-05-7
Molecular Formula	C22H36O3Si
Molecular Weight	376.61 g/mol
Synonyms	7α-(Trimethylsilyloxy)androst-4-ene-3,17-dione; 7α-TMS-Androstenedione; Androst-4-ene-3,17-dione, 7-(trimethylsilyloxy)-, (7α)-; 7α-Hydroxyandrost-4-ene-3,17-dione trimethylsilyl ether; 7α-TMS-AD; 7α-(Trimethylsiloxy)-4-androstene-3,17-dione
EINECS	Contact for details

Quality Control

Our 7α-(Trimethylsiloxy)Androst-4-Ene-3,17-Dione is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.