Description

3-(2-Chloroethyl)-1-(3-Hydroxypropyl)-3-Nitrosourea CAS NO 60784-47-6 is a specialized nitrosourea derivative, a class of compounds known for their alkylating activity. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a key intermediate or active moiety. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, especially in the fields of oncology and experimental chemotherapy. Its unique structure allows for targeted chemical modifications in drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel alkylating chemotherapeutic agents and experimental drugs.
• Oncology Research: Used in biochemical and pharmacological research to study the mechanisms of DNA alkylation and cytotoxicity in cancer cell lines.
• Medicinal Chemistry: Acts as a precursor for the development of prodrugs and targeted drug delivery systems due to its reactive functional groups.
• Biochemical Tool Compound: Employed in laboratory studies to investigate the biological effects of nitrosourea compounds on cellular processes.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for synthetic organic chemistry projects and biological screening.
• API Development: Potential use in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs) with alkylating properties.

Basic Information

Product Name	3-(2-Chloroethyl)-1-(3-Hydroxypropyl)-3-Nitrosourea
CAS No.	60784-47-6
Molecular Formula	C6H12ClN3O3
Molecular Weight	209.63 g/mol
Synonyms	1-(3-Hydroxypropyl)-3-(2-chloroethyl)-1-nitrosourea; 3-(2-Chloroethyl)-1-(3-hydroxypropyl)-1-nitrosourea; N-(2-Chloroethyl)-N'-nitroso-N-(3-hydroxypropyl)urea; HECNU; Hydroxyethyl Chloroethyl Nitrosourea; Nitrosourea HECNU; NSC 294885
EINECS	Contact for details

Quality Control

Our 3-(2-Chloroethyl)-1-(3-Hydroxypropyl)-3-Nitrosourea is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.