Description

1,1'-Pentamethylenebis[3-(2-Chloroethyl)-3-Nitrosourea] is a specialized bifunctional alkylating agent belonging to the nitrosourea class of compounds. This chemical is of significant interest in advanced research and development due to its potential as a cross-linking agent and its biological activity profile. It is primarily utilized by researchers and development teams in the pharmaceutical and life sciences sectors. The compound is recognized under the registry number CAS 60784-44-3.

Application

• Pharmaceutical Research: Investigated as a potential precursor or active pharmaceutical ingredient (API) in oncology research, particularly for its alkylating properties.
• Biochemical Studies: Used as a cross-linking agent in proteomics and molecular biology to study protein-protein interactions and nucleic acid structures.
• Chemical Synthesis: Serves as a key intermediate in the synthesis of more complex nitrosourea derivatives and other specialized organic compounds.
• Material Science: Explored for modifying polymer chains to create novel materials with specific functional properties.
• Anticancer Agent Development: Studied for its mechanism of action and efficacy in preclinical models for various cancer types.
• Laboratory Reagent: Employed as a high-purity standard or reagent in analytical and experimental protocols requiring nitrosourea chemistry.

Basic Information

Item	Detail
Product Name	1,1'-Pentamethylenebis[3-(2-Chloroethyl)-3-Nitrosourea]
CAS No.	60784-44-3
Molecular Formula	C13H22Cl2N6O4
Molecular Weight	401.26 g/mol
Synonyms	1,1'-(Pentane-1,5-diyl)bis[3-(2-chloroethyl)-1-nitrosourea]; 1,5-Bis[3-(2-chloroethyl)-3-nitrosoureido]pentane; NSC 95466; BCNU Dimer; Pentamethylene bis(1-(2-chloroethyl)-1-nitrosourea); 1,1'-Pentamethylenebis(1-(2-chloroethyl)-1-nitrosourea); Chloroethyl Nitrosourea Dimer
EINECS	Contact for details

Quality Control

Every batch of 1,1'-Pentamethylenebis[3-(2-Chloroethyl)-3-Nitrosourea] is manufactured and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere to prevent oxidation and moisture uptake. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.