Description

1,1'-Tetramethylenebis[3-(2-Chloroethyl)-3-Nitrosourea] is a specialized bifunctional alkylating agent belonging to the nitrosourea class of compounds. This chemical is of significant interest in advanced research and development, particularly for its potential as a key intermediate in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in oncology drug discovery and the development of targeted chemotherapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of experimental anticancer drugs and other bioactive molecules.
• Biomedical Research: Used in biochemical and pharmacological studies to investigate alkylation mechanisms and DNA cross-linking agents.
• Antineoplastic Agent Development: Acts as a core structural component for developing new nitrosourea-based chemotherapeutic candidates.
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) in medicinal chemistry.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.

Basic Information

Product Name	1,1'-Tetramethylenebis[3-(2-Chloroethyl)-3-Nitrosourea]
CAS No.	60784-43-2
Molecular Formula	C12H20Cl2N6O4
Molecular Weight	383.23 g/mol
Synonyms	1,1'-(Tetramethylene)bis[1-(2-chloroethyl)-1-nitrosourea]; BCNU Dimer; Carmustine Dimer; 1,1'-Butanediylbis[3-(2-chloroethyl)-3-nitrosourea]; NSC 85998; Nitrosourea Dimer; Bis(2-chloroethylnitrosocarbamoyl)butane
EINECS	Contact for details

Quality Control

Our 1,1'-Tetramethylenebis[3-(2-Chloroethyl)-3-Nitrosourea] is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.