Description

1,1'-Propylenebis[3-(2-Chloroethyl)-3-Nitrosourea] is a specialized bifunctional nitrosourea compound of significant interest in advanced chemical synthesis and research. This compound matters for its role as a key intermediate or active moiety in the development of targeted agents, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical development companies engaged in the synthesis of novel therapeutic candidates, especially within oncology and targeted drug delivery systems.

Application

• Research and development of novel alkylating antineoplastic agents.
• Key synthetic intermediate in medicinal chemistry for oncology drug discovery.
• Building block for the synthesis of targeted polymer-drug conjugates.
• Precursor in biochemical research involving DNA cross-linking studies.
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• Intermediate for specialized fine chemicals and advanced material science applications.

Basic Information

Product Name	1,1'-Propylenebis[3-(2-Chloroethyl)-3-Nitrosourea]
CAS No.	60784-42-1
Molecular Formula	C11H18Cl2N6O4
Molecular Weight	369.21 g/mol
Synonyms	1,1'-(Propane-1,3-diyl)bis[3-(2-chloroethyl)-1-nitrosourea]; 1,3-Bis[3-(2-chloroethyl)-3-nitrosoureido]propane; Propylenebis(chloroethylnitrosourea); PCNU (common abbreviation); Bifunctional Nitrosourea Derivative; 1,1'-Trimethylenebis(1-(2-chloroethyl)-1-nitrosourea); NSC 95466
EINECS	Contact for details

Quality Control

Our 1,1'-Propylenebis[3-(2-Chloroethyl)-3-Nitrosourea] is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.