Description

4,6-Dimethylisothiazolo[5,4-B]Pyridin-3(2H)-One is a high-purity, fused heterocyclic compound that serves as a critical advanced intermediate in organic synthesis. Its unique isothiazolopyridine scaffold makes it a valuable building block for developing novel active pharmaceutical ingredients (APIs) and functional materials. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a precursor for developing organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: A versatile starting material for method development and exploration of new chemical spaces in synthetic organic chemistry laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	4,6-Dimethylisothiazolo[5,4-B]Pyridin-3(2H)-One
CAS No.	60750-75-6
Molecular Formula	C9H8N2OS
Molecular Weight	192.24 g/mol
Synonyms	4,6-Dimethylisothiazolo[5,4-b]pyridin-3(2H)-one; 3H-Isothiazolo[5,4-b]pyridin-3-one, 4,6-dimethyl-; 4,6-Dimethyl-3H-isothiazolo[5,4-b]pyridin-3-one; 4,6-Dimethylisothiazolopyridinone; 2H-4,6-Dimethylisothiazolo[5,4-b]pyridin-3-one
EINECS	Contact for details

Quality Control

Our 4,6-Dimethylisothiazolo[5,4-B]Pyridin-3(2H)-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.