Description

5-(2-Bromo-Acetyl)-Nicotinic Acid Methyl Esterhydrobromide is a high-purity brominated nicotinic acid derivative, serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its reactive bromoacetyl and ester functional groups, enabling precise molecular construction in complex synthesis pathways. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly in medicinal chemistry research for new therapeutic agents.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides requiring specific heterocyclic structures.
• Chemical Research & Development: Essential reagent for academic and industrial research in organic synthesis, methodology development, and material science.
• Ligand and Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Fine Chemical Production: Intermediate in the manufacture of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	5-(2-Bromo-Acetyl)-Nicotinic Acid Methyl Esterhydrobromide
CAS No.	60699-65-2
Molecular Formula	C9H9Br2NO3
Molecular Weight	339.98 g/mol
Synonyms	Methyl 5-(2-bromoacetyl)nicotinate hydrobromide; 5-(Bromoacetyl)nicotinic Acid Methyl Ester HBr; 2-Bromo-1-(5-(methoxycarbonyl)pyridin-3-yl)ethan-1-one hydrobromide; Nicotinic acid, 5-(2-bromoacetyl)-, methyl ester, hydrobromide; Methyl 5-(2-bromoacetyl)pyridine-3-carboxylate hydrobromide; 60699-65-2; 5-(2-Bromoacetyl)-3-pyridinecarboxylic acid methyl ester hydrobromide
EINECS	Contact for details

Quality Control

Our 5-(2-Bromo-Acetyl)-Nicotinic Acid Methyl Esterhydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to exclude moisture and stored away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.