Description

3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-5-Thiazolidineethanol Dihydrogen Phosphate is a high-purity, phosphate ester derivative of a thiazolidineethanol compound, serving as a critical pharmaceutical intermediate and biochemical reagent. Its primary commercial value lies in its role as a key precursor or active moiety in the synthesis of specialized therapeutic agents and research compounds. This product is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise molecular building blocks.

Application

• Pharmaceutical Intermediate: A vital building block in the synthesis of novel drug candidates, particularly those targeting metabolic or neurological pathways.
• Biochemical Research: Used as a reference standard or reagent in enzymatic studies and metabolic pathway analysis.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core structural component in the production of specific, potentiated therapeutic agents.
• Veterinary Medicine Development: Employed in the research and formulation of advanced veterinary pharmaceuticals.
• Diagnostic Reagent Manufacturing: Utilized in the production of specialized diagnostic kits and assays.
• Academic & Industrial R&D: Fundamental for chemical biology research and the development of new chemical entities in corporate and university laboratories.

Basic Information

Product Name	3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-5-Thiazolidineethanol Dihydrogen Phosphate
CAS No.	60689-64-7
Molecular Formula	C12H21N4O4PS
Molecular Weight	348.36 g/mol
Synonyms	Thiamine Phosphate Ester; Vitamin B1 Phosphate; Thiamine Monophosphate (TMP); 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium Phosphate; Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, phosphate (1:1); Thiamine Dihydrogen Phosphate; Thiamine Acid Phosphate; Cocarboxylase precursor
EINECS	Contact for details

Quality Control

Our 3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-5-Thiazolidineethanol Dihydrogen Phosphate is manufactured under strict quality management systems. Products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We can support development and commercial projects requiring compliance with cGMP, ICH guidelines, and relevant pharmacopeial standards (USP/EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Long-term storage under inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.