Description

1-[(2-Chloro-3-Pyridinyl)Carbonyl]-4-Methylpiperazine is a high-purity, advanced pharmaceutical intermediate characterized by its specific heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the research and development of next-generation insecticides and pesticides, leveraging its pyridine and piperazine motifs.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling the exploration of new chemical entities and structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the commercial-scale production of specific APIs where its unique molecular framework is integral to the final drug's activity.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects and process development.

Basic Information

Product Name	1-[(2-Chloro-3-Pyridinyl)Carbonyl]-4-Methylpiperazine
CAS No.	60597-69-5
Molecular Formula	C12H14ClN3O
Molecular Weight	251.71 g/mol
Synonyms	4-Methyl-1-[(2-chloro-3-pyridinyl)carbonyl]piperazine; 2-Chloro-N-(4-methylpiperazin-1-yl)nicotinamide; 1-(2-Chloronicotinoyl)-4-methylpiperazine; 2-Chloro-3-(4-methylpiperazine-1-carbonyl)pyridine; 60597-69-5; UNII-8Q2QZP5F6T; 8Q2QZP5F6T
EINECS	Contact for details

Quality Control

Our 1-[(2-Chloro-3-Pyridinyl)Carbonyl]-4-Methylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.