Description

2-Cyano-1-Cyclopentyl-3-(3-Pyridyl)Guanidine is a specialized organic compound featuring a guanidine core functionalized with cyano, cyclopentyl, and pyridyl groups, making it a valuable intermediate for advanced chemical synthesis. This compound is critical for research and development in the pharmaceutical sector, particularly in the creation of novel drug candidates targeting specific biological pathways. It is primarily utilized by fine chemical manufacturers, contract research organizations (CROs), and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential therapeutic agents, particularly for central nervous system (CNS) and cardiovascular targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique guanidine scaffold.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study enzyme inhibition and receptor-ligand interactions.
• Process Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Custom Synthesis: Basis for producing bespoke compounds and libraries for high-throughput screening in drug discovery.
• Academic Research: Utilized in university and institutional labs for investigating novel heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	2-Cyano-1-Cyclopentyl-3-(3-Pyridyl)Guanidine
CAS No.	60560-22-7
Molecular Formula	C12H15N5
Molecular Weight	229.28 g/mol
Synonyms	1-Cyclopentyl-2-cyano-3-(3-pyridyl)guanidine; 3-Pyridylguanidine derivative; N-Cyano-N'-cyclopentyl-N''-(3-pyridinyl)guanidine; Guanidine, N-cyano-N'-cyclopentyl-N''-3-pyridinyl-; 2-Cyano-1-cyclopentyl-3-(pyridin-3-yl)guanidine; (3-Pyridyl)-N-cyano-N'-cyclopentylguanidine; Research Code Compound (various); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 2-Cyano-1-Cyclopentyl-3-(3-Pyridyl)Guanidine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for use under cGMP guidelines for non-clinical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.