Description

3-Pyridyl Pinacidil is a specialized chemical intermediate and research compound of significant interest in medicinal chemistry and pharmaceutical development. Its value lies in its structural role as a key synthon for creating novel compounds targeting potassium channel modulation. This product is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing cardiovascular therapeutics and exploring ion channel physiology.

Application

• Pharmaceutical Research & Development (R&D): Serves as a critical building block (synthon) for the synthesis of novel potassium channel openers and related pharmacologically active molecules.
• Medicinal Chemistry Studies: Used in structure-activity relationship (SAR) studies to develop new chemical entities with potential vasodilatory and cardioprotective properties.
• Reference Standard: Employed as an analytical standard in quality control and method development for laboratories analyzing pinacidil derivatives and related compounds.
• Biochemical Research: Utilized in vitro and ex vivo studies to investigate the mechanisms of ATP-sensitive potassium (KATP) channels in various tissues.
• Fine Chemical Synthesis: Acts as a high-value intermediate for contract research organizations (CROs) and custom synthesis manufacturers producing specialized compounds for client projects.

Basic Information

Product Name	3-Pyridyl Pinacidil
CAS No.	60560-07-8
Molecular Formula	C13H19N5O
Molecular Weight	261.33 g/mol
Synonyms	N-Cyano-N'-(3-pyridyl)-N''-(1,2,2-trimethylpropyl)guanidine; 3-Pyridylpinacidil; Pinacidil 3-Pyridyl Analog; 1-(3-Pyridinyl)-2-[(1,2,2-trimethylpropyl)amino]-2-cyanoguanidine; N''-Cyano-N-(3-pyridinyl)-N'-(1,2,2-trimethylpropyl)guanidine; N-Cyano-N'-(3-pyridyl)-N''-(1,2,2-trimethylpropyl)guanidine; Guanidine, N-cyano-N'-(3-pyridinyl)-N''-(1,2,2-trimethylpropyl)-
EINECS	Contact for details

Quality Control

Our 3-Pyridyl Pinacidil is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.