Description

Benzyl 5-Oxoprolinate (CAS NO 60555-57-9) is a protected amino acid derivative that serves as a crucial chiral building block in advanced organic synthesis. This compound is valued for its role in constructing complex peptide mimetics and active pharmaceutical ingredients (APIs), offering precise stereochemical control. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of peptide-based drugs and protease inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides with specific chiral activity.
• Peptide Chemistry: Serves as a protected proline analog for solid-phase and solution-phase peptide synthesis.
• Bioconjugation: Employed in the preparation of labeled peptides and protein conjugates for diagnostic applications.
• Academic & Industrial Research: A valuable reagent for methodological development in asymmetric synthesis and medicinal chemistry.
• Fine Chemical Production: Used in the manufacture of specialty chemicals requiring high-purity chiral intermediates.

Basic Information

Product Name	Benzyl 5-Oxoprolinate
CAS No.	60555-57-9
Molecular Formula	C12H13NO3
Molecular Weight	219.24 g/mol
Synonyms	Benzyl 5-oxopyrrolidine-2-carboxylate; 5-Oxo-L-proline benzyl ester; 5-Oxoproline benzyl ester; Pyroglutamic acid benzyl ester; (S)-(-)-Pyroglutamic acid benzyl ester; L-Pyroglutamic acid benzyl ester; Benzyl L-pyroglutamate
EINECS	Contact for details

Quality Control

Our Benzyl 5-Oxoprolinate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.