Description

4-(2-Methyl-1,3-dioxolan-2-yl)pyridine is a versatile heterocyclic building block featuring a pyridine ring protected by a 2-methyl-1,3-dioxolane group. This compound matters as a key synthetic intermediate, offering a protected aldehyde equivalent that is stable under a wide range of reaction conditions, enabling precise chemical transformations. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those containing functionalized pyridine or nicotinic acid derivatives.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators where the pyridine moiety is a key pharmacophore.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, due to its electron-deficient pyridine ring.
• Chemical Biology Probes: Acts as a building block for creating molecular probes and tags used in bio-conjugation and diagnostic assay development.
• Fine Chemical Production: Utilized in multi-step syntheses for producing high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	4-(2-Methyl-1,3-dioxolan-2-yl)pyridine
CAS No.	60553-33-5
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	2-(Pyridin-4-yl)-2-methyl-1,3-dioxolane; 4-(2-Methyl-1,3-dioxolan-2-yl)pyridine; 4-(2-Methyl-[1,3]dioxolan-2-yl)-pyridine; 4-(2-Methyl-1,3-dioxolan-2-yl)pyridine; Pyridine, 4-(2-methyl-1,3-dioxolan-2-yl)-; 4-Pyridylacetaldehyde dimethyl acetal (protected form); 4-(2-Methyl-1,3-dioxolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 4-(2-Methyl-1,3-dioxolan-2-yl)pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.