Description

Cyanoacetic Acid Trimethylsilyl Ester is a versatile organosilicon reagent primarily used as a key building block in organic synthesis. Its value lies in its dual functionality, where the trimethylsilyl group acts as a protective moiety and the cyanoacetate moiety serves as a reactive site for condensation and cyclization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for synthesizing heterocyclic compounds, fine chemicals, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediates: A critical precursor in the synthesis of various heterocyclic compounds, including pyrimidines and pyridines, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its reactive cyanoacetate group is utilized to construct complex molecular frameworks.
• Fine Chemical Production: Serves as a versatile reagent for Knoevenagel condensations and other carbon-carbon bond-forming reactions to create specialty chemicals and dyes.
• Silicon Chemistry: Acts as a silylating agent and a protected form of cyanoacetic acid, facilitating specific synthetic pathways where the free acid would be incompatible.
• Material Science Research: Employed in the development of novel organic materials and polymers that incorporate silicon and cyano functional groups.

Basic Information

Product Name	Cyanoacetic Acid Trimethylsilyl Ester
CAS No.	60511-70-8
Molecular Formula	C6H11NO2Si
Molecular Weight	157.24 g/mol
Synonyms	Trimethylsilyl Cyanoacetate; (Trimethylsilyl) Cyanoacetate; Cyanoacetic Acid TMS Ester; TMS Cyanoacetate; Cyanoacetic Acid Trimethylsilyl Ester; Trimethylsilyl Cyanoethanoate; NSC 334076; 2-Cyanoacetic Acid Trimethylsilyl Ester
EINECS	Contact for details

Quality Control

Our Cyanoacetic Acid Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.