Description

Alpha,β-Isopropylidene-L-Glyceric Acid Methyl Ester is a protected chiral synthon of significant value in asymmetric organic synthesis. This compound serves as a versatile building block for the construction of complex molecules, particularly in the pharmaceutical and fine chemical industries. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), nucleoside analogs, and other high-value chiral intermediates where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of antiviral agents, nucleoside drugs, and other therapeutic compounds.
• Asymmetric Synthesis: Used as a starting material or chiral auxiliary in stereoselective reactions to introduce specific configurations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry.
• Agrochemical Synthesis: Potential use in creating chiral active ingredients for advanced crop protection products.

Basic Information

Product Name	Alpha,β-Isopropylidene-L-Glyceric Acid Methyl Ester
CAS No.	60456-21-5
Molecular Formula	C8H14O5
Molecular Weight	190.19 g/mol
Synonyms	(R)-2,2-Dimethyl-1,3-dioxolane-4-acetic acid methyl ester; L-(+)-2,3-O-Isopropylideneglyceric acid methyl ester; Methyl (R)-2,2-dimethyl-1,3-dioxolane-4-acetate; Methyl (R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate; (4R)-2,2-Dimethyl-1,3-dioxolane-4-acetic acid methyl ester; L-Glyceric acid, 2,3-O-isopropylidene-, methyl ester; Methyl 2,3-O-isopropylidene-L-glycerate
EINECS	Contact for details

Quality Control

Our Alpha,β-Isopropylidene-L-Glyceric Acid Methyl Ester is produced under strict quality management systems. We offer material with high chiral purity, typically ≥98% (by chiral HPLC), and provide comprehensive analytical data. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch to ensure compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.