Description

R-Methyl 1-Cbz-Piperidine-2-Carboxylate is a high-purity chiral piperidine derivative, serving as a critical building block in advanced organic synthesis. This compound is essential for the development of novel pharmaceutical intermediates and fine chemicals, offering a versatile scaffold for medicinal chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for creating complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Peptidomimetic Research: Used in the design and construction of peptide analogs and protease inhibitors due to its constrained piperidine structure.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for developing novel chiral ligands and organocatalysts.
• Agrochemical Synthesis: Employed in the research and production of advanced, enantiomerically pure crop protection agents.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	R-Methyl 1-Cbz-Piperidine-2-Carboxylate
CAS No.	60369-19-9
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	(R)-Methyl 1-[(benzyloxy)carbonyl]piperidine-2-carboxylate; (R)-1-Cbz-Piperidine-2-Carboxylic Acid Methyl Ester; Methyl (R)-1-[(benzyloxy)carbonyl]piperidine-2-carboxylate; (R)-1-(Benzyloxycarbonyl)piperidine-2-carboxylic Acid Methyl Ester; (R)-N-Cbz-Pipecolic Acid Methyl Ester; (R)-1-CBZ-2-Piperidinecarboxylic Acid Methyl Ester; (R)-Piperidine-2-carboxylic acid, 1-[(phenylmethoxy)carbonyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our R-Methyl 1-Cbz-Piperidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.