Description

Murametide is a synthetic immunomodulatory peptide, specifically a derivative of muramyl dipeptide (MDP), known for its potent biological activity. This compound is a critical intermediate and research tool in the development of novel vaccine adjuvants and immunotherapies. It is primarily utilized by pharmaceutical R&D departments, biotechnology firms, and academic research institutions focused on immunology and vaccine development.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of advanced immunomodulators and vaccine adjuvants.
• Immunology Studies: Used as a reference standard or active component in *in vitro* and *in vivo* studies to investigate innate immune responses via NOD2 receptor activation.
• Vaccine Adjuvant Development: Serves as a building block for creating next-generation adjuvants to enhance the efficacy of prophylactic and therapeutic vaccines.
• Bioconjugation: Employed in the development of conjugate vaccines and targeted immunotherapies due to its modifiable structure.
• Cell Culture & Stimulation: Used to stimulate immune cells in culture to study cytokine production and cellular activation pathways.

Basic Information

Product Name	Murametide
CAS No.	60355-78-4
Molecular Formula	C20H34N4O10
Molecular Weight	490.50 g/mol
Synonyms	N-Acetylmuramyl-L-alanyl-D-isoglutamine methyl ester; MDP-Lys(L18); L18-MDP; Muramyl dipeptide lysine derivative; Romurtide (related compound); Immunomodulator peptide; Adjuvant peptide; NSC 324366
EINECS	Contact for details

Quality Control

Our Murametide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, chiral purity, and related substances. Production can adhere to cGMP guidelines for advanced research and pre-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.