Description

6-Nitropyridine-2-Carboxamide is a specialized heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyridine-nitrogen pharmacophore.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as electron-transport layers and non-linear optical (NLO) chromophores.
• Chemical Biology Probes: Utilized as a scaffold for developing enzyme inhibitors and molecular probes for biochemical pathway analysis.
• Academic & Contract Research: A valuable reagent for methodology development and exploratory synthetic chemistry in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	6-Nitropyridine-2-Carboxamide
CAS No.	60278-80-0
Molecular Formula	C6H5N3O3
Molecular Weight	167.12 g/mol
Synonyms	2-Pyridinecarboxamide, 6-nitro-; 6-Nitro-2-pyridinecarboxamide; 6-Nitropicolinamide; 2-Carbamoyl-6-nitropyridine; 6-Nitropyridine-2-carboxylic acid amide; Picolinamide, 6-nitro-; 6-Nitro-2-pyridylcarboxamide
EINECS	Contact for details

Quality Control

Our 6-Nitropyridine-2-Carboxamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.