Description

1-Fluoro-3-Isocyanato-2-Methyl-Benzene is a versatile aromatic isocyanate building block used in advanced organic synthesis. Its value lies in the reactive isocyanate group, which readily undergoes addition reactions with nucleophiles like amines and alcohols to form ureas and urethanes, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries who require a fluorinated aromatic precursor for developing new active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring a fluorinated aromatic moiety to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental persistence.
• Polymer & Resin Modification: Serves as a cross-linking agent or chain extender in the manufacture of polyurethanes, polyureas, and other specialty polymers, imparting specific chemical resistance or thermal properties.
• Chemical Research & Development: A critical reagent in organic chemistry labs for constructing heterocycles, urea derivatives, and other complex organic molecules for material science and medicinal chemistry projects.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized colorants and optical brighteners.

Basic Information

Product Name	1-Fluoro-3-Isocyanato-2-Methyl-Benzene
CAS No.	60221-81-0
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	2-Methyl-6-fluorophenyl isocyanate; 6-Fluoro-2-methylphenyl isocyanate; 2-Fluoro-6-isocyanatotoluene; 3-Fluoro-2-methylphenyl isocyanate; 2-Methyl-3-fluorophenyl isocyanate; 1-Isocyanato-3-fluoro-2-methylbenzene; 3-Fluoro-o-tolyl isocyanate
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-Isocyanato-2-Methyl-Benzene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (IR, NMR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.