Description

Dimethyl Acetamidomalonate is a versatile and high-purity chemical building block, essential for the synthesis of complex organic molecules. Its primary value lies in its role as a key precursor for introducing the acetamidomalonate moiety, a crucial step in the preparation of α-amino acids and heterocyclic compounds. This product is critically needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for advanced synthetic applications.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of non-proteinogenic α-amino acids and peptide mimetics used in drug discovery and development.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific amino acid derivatives.
• Fine Chemical Production: Serves as a versatile building block for creating complex molecules used in catalysts, ligands, and specialty materials.
• Research & Development: Utilized in academic and industrial R&D labs for method development and the synthesis of novel organic compounds.
• Peptidomimetic Chemistry: Integral for constructing peptide analogs with enhanced stability or biological activity for therapeutic applications.

Basic Information

Product Name	Dimethyl Acetamidomalonate
CAS No.	60187-67-9
Molecular Formula	C7H11NO5
Molecular Weight	189.17 g/mol
Synonyms	Dimethyl 2-Acetamidomalonate; Acetamidomalonic Acid Dimethyl Ester; Dimethyl (Acetylamino)malonate; 2-Acetamidomalonic Acid Dimethyl Ester; Acetamidomalonic Ester; DAM; Dimethyl Aminomalonate, N-Acetyl-
EINECS	262-170-9

Quality Control

Our Dimethyl Acetamidomalonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We adhere to current Good Manufacturing Practices (cGMP) where applicable. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); therefore, containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.