Description

3H-Imidazo[4,5-C]Pyridine, 4,6-Difluoro- is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibition and other therapeutic areas. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise chemical scaffold to construct complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel fluorinated compounds for potential use in crop protection agents and pesticides.
• Material Science Precursor: Serves as a building block for creating specialized fluorinated organic materials, such as ligands for catalysis or components for organic electronics.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Academic & Industrial R&D: Essential for synthetic chemistry research in universities and corporate labs focused on heterocyclic and fluorine chemistry.

Basic Information

Product Name	3H-Imidazo[4,5-C]Pyridine, 4,6-Difluoro-
CAS No.	60186-30-3
Molecular Formula	C6H3F2N3
Molecular Weight	155.11 g/mol
Synonyms	4,6-Difluoro-3H-imidazo[4,5-c]pyridine; 4,6-Difluoro-1H-imidazo[4,5-c]pyridine; 4,6-Difluoroimidazo[4,5-c]pyridine; 1H-Imidazo[4,5-c]pyridine, 4,6-difluoro-; 4,6-Difluoro-3H-imidazo[4,5-c]pyridin; 60186-30-3; 4,6-Difluoroimidazopyridine
EINECS	Contact for details

Quality Control

Our 3H-Imidazo[4,5-C]Pyridine, 4,6-Difluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.