Description

2,6-Difluoropyridine-3,4-Diamine is a high-purity, multi-functional aromatic amine building block featuring a fluorinated pyridine core. This compound is valued for its unique reactivity profile, enabling the synthesis of complex heterocyclic systems and advanced materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and metabolic stability.
• Ligand & Catalyst Development: Serves as a versatile scaffold for constructing nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Functional Material Precursor: Employed in the research and production of advanced materials, including organic semiconductors, liquid crystals, and dyes.
• Chemical Research & Development: A valuable building block for medicinal chemistry, process R&D, and library synthesis in academic and industrial laboratories.

Basic Information

Product Name	2,6-Difluoropyridine-3,4-Diamine
CAS No.	60186-25-6
Molecular Formula	C5H5F2N3
Molecular Weight	145.11 g/mol
Synonyms	3,4-Diamino-2,6-difluoropyridine; 2,6-Difluoro-3,4-pyridinediamine; 2,6-Difluoropyridine-3,4-diyldiamine; 3,4-Pyridinediamine, 2,6-difluoro-; 2,6-Difluoro-3,4-diaminopyridine; 2,6-Difluor-3,4-diaminopyridin (German); 2,6-ジフルオロピリジン-3,4-ジアミン (Japanese)
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluoropyridine-3,4-Diamine is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.