Description

2,4,6-Trifluoro-3-nitropyridine is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoro-nitro substitution pattern makes it a valuable precursor for introducing fluorine atoms and functional groups into complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and electronic materials that benefit from fluorinated aromatic systems.
• Organic Synthesis Building Block: Facilitates nucleophilic aromatic substitution reactions, allowing for the selective introduction of amines, alkoxides, and other nucleophiles.
• Chemical Research & Development: Serves as a standard reagent in academic and industrial R&D labs for exploring new fluorination methodologies and heterocyclic chemistry.

Basic Information

Product Name	2,4,6-Trifluoro-3-nitropyridine
CAS No.	60186-17-6
Molecular Formula	C5H2F3N2O2
Molecular Weight	179.08 g/mol
Synonyms	3-Nitro-2,4,6-trifluoropyridine; 2,4,6-Trifluoro-3-nitro-pyridine; Pyridine, 2,4,6-trifluoro-3-nitro-; 2,4,6-Trifluoronicotinic acid nitro derivative (intermediate)
EINECS	Contact for details

Quality Control

Our 2,4,6-Trifluoro-3-nitropyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.